Physiological and genetic analyses of inbred mouse strains with a type I iodothyronine 5' deiodinase deficiency.

Inbred mouse strains differ in their capacity to deiodinate iododioxin and iodothyronines, with strains segregating into high or low activity groups. Metabolism of iododioxin occurs via the type I iodothyronine 5'deiodinase (5'DI), one of two enzymes that metabolize thyroxine (T4) to 3,5,3'-triiodot...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Berry, M J, Grieco, D, Taylor, B A, Maia, A L, Kieffer, J D, Beamer, W, Glover, E, Poland, A, Larsen, P R
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288298/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8104199/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116730
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