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A comprehensive survey of human polymorphisms at conserved splice dinucleotides and its evolutionary relationship with alternative splicing

BACKGROUND: Alternative splicing (AS) is a key molecular process that endows biological functions with diversity and complexity. Generally, functional redundancy leads to the generation of new functions through relaxation of selective pressure in evolution, as exemplified by duplicated genes. It is...

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Bibliografski detalji
Glavni autori: Shimada, Makoto K, Hayakawa, Yosuke, Takeda, Jun-ichi, Gojobori, Takashi, Imanishi, Tadashi
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882926/
https://ncbi.nlm.nih.gov/pubmed/20433709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-10-122
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