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A comprehensive survey of human polymorphisms at conserved splice dinucleotides and its evolutionary relationship with alternative splicing

BACKGROUND: Alternative splicing (AS) is a key molecular process that endows biological functions with diversity and complexity. Generally, functional redundancy leads to the generation of new functions through relaxation of selective pressure in evolution, as exemplified by duplicated genes. It is...

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Main Authors: Shimada, Makoto K, Hayakawa, Yosuke, Takeda, Jun-ichi, Gojobori, Takashi, Imanishi, Tadashi
格式: Artigo
語言:Inglês
出版: BioMed Central 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882926/
https://ncbi.nlm.nih.gov/pubmed/20433709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-10-122
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