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A comprehensive survey of human polymorphisms at conserved splice dinucleotides and its evolutionary relationship with alternative splicing

BACKGROUND: Alternative splicing (AS) is a key molecular process that endows biological functions with diversity and complexity. Generally, functional redundancy leads to the generation of new functions through relaxation of selective pressure in evolution, as exemplified by duplicated genes. It is...

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Main Authors: Shimada, Makoto K, Hayakawa, Yosuke, Takeda, Jun-ichi, Gojobori, Takashi, Imanishi, Tadashi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882926/
https://ncbi.nlm.nih.gov/pubmed/20433709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-10-122
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