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Distribution and Effects of Nonsense Polymorphisms in Human Genes

BACKGROUND: A great amount of data has been accumulated on genetic variations in the human genome, but we still do not know much about how the genetic variations affect gene function. In particular, little is known about the distribution of nonsense polymorphisms in human genes despite their drastic...

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Detalhes bibliográficos
Main Authors: Yamaguchi-Kabata, Yumi, Shimada, Makoto K., Hayakawa, Yosuke, Minoshima, Shinsei, Chakraborty, Ranajit, Gojobori, Takashi, Imanishi, Tadashi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2561068/
https://ncbi.nlm.nih.gov/pubmed/18852891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003393
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