ACTIVATION OF PERK KINASE IN NEURAL CELLS BY PROTEASOME INHIBITOR TREATMENT

Inhibition of the proteasome proteolytic pathway occurs as the result of normal aging, as well as in a variety of neurodegenerative conditions, and is believed to promote cellular toxicity in each of these conditions through diverse mechanisms. In the present study we examined whether proteasome inh...

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Bibliographic Details
Main Authors: Zhang, Le, Ebenezer, Philip J, Dasuri, Kalavathi, Bruce-Keller, Annadora J., Fernandez-Kim, Sun Ok, Liu, Ying, Keller, Jeffrey N.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882876/
https://ncbi.nlm.nih.gov/pubmed/19860852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2009.06448.x
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