PROTEASOME INHIBITION MODULATES KINASE ACTIVATION IN NEURAL CELLS: RELEVENCE TO UBIQUITINATION, RIBOSOMES, AND SURVIVAL

In this study we examined whether established signal transduction cascades, p44/42 mitogen activated protein kinase (ERK1/2) and Jun N-terminal kinases (JNK) pathways, are altered in N2a neural cells in response to proteasome inhibition. Additionally, we sought to elucidate the relative contribution...

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Main Authors: Zhang, Le, Ebenezer, Philip J, Dasuri, Kalavathi, Bruce-Keller, Annadora J., Liu, Ying, Keller, Jeffrey N.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875064/
https://ncbi.nlm.nih.gov/pubmed/19565657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.22147
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