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Crystallization and preliminary X-ray diffraction analysis of the complex of a human anti-ephrin type-A receptor 2 antibody fragment and its cognate antigen
The recombinant N-terminal domain of human ephrin type-A receptor 2 (rEphA2) has been crystallized in complex with the recombinantly produced Fab fragment of a fully human antibody (1C1; IgG1/κ). These are the first reported crystals of an ephrin receptor bound to an antibody. The orthorhombic cryst...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
International Union of Crystallography
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2882782/ https://ncbi.nlm.nih.gov/pubmed/20516612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309110015861 |
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