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Diabetes reduces the cholesterol exporter ABCA1 in mouse macrophages and kidneys1

Accumulation of cholesterol in arterial macrophages may contribute to diabetes-accelerated atherosclerotic cardiovascular disease. The ATP-binding cassette transporter ABCA1 is a cardioprotective membrane protein that mediates cholesterol export from macrophages. Factors elevated in diabetes, such a...

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Autori principali: Tang, Chongren, Kanter, Jenny E., Bornfeldt, Karin E., Leboeuf, Renee C., Oram, John F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882721/
https://ncbi.nlm.nih.gov/pubmed/19965614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M003525
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