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ADAM17 boosts cholesterol efflux and downstream effects of HDL on inflammatory pathways in macrophages
OBJECTIVE: High-density lipoprotein (HDL) can exert both anti-inflammatory and pro-inflammatory effects in macrophages due to its ability to induce cholesterol depletion. Because cholesterol depletion also increases sheddase activity of the membrane protease ADAM17 (ADAM metallopeptidase domain 17)...
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| Pubblicato in: | Arterioscler Thromb Vasc Biol |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8159900/ https://ncbi.nlm.nih.gov/pubmed/33882688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.121.315145 |
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