Identification of unique nuclear regulatory proteins for the insulin receptor gene, which appear during myocyte and adipocyte differentiation.

To define the molecular mechanism(s) that activate insulin receptor gene transcription during cell differentiation, we tested nuclear extracts from BC3H-1 muscle cells for their binding to the 5'-flanking region of the human insulin receptor gene. DNA binding activity of nuclear extracts was low in...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Brunetti, A, Foti, D, Goldfine, I D
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1993
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288270/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8376587/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116702
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