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One-electron oxidation of DNA by ionizing radiation: competition between base-to-base hole-transfer and hole-trapping

The distance of hole migration through DNA determines the degree to which radiation induced lesions are clustered. It is the degree of clustering that confers to ionizing radiation its high toxicity. The migration distance is governed by a competition between hole transfer and irreversible trapping...

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Detalhes bibliográficos
Main Authors: Sharma, Kiran K. K., Tyagi, Rahul, Purkayastha, Shubhadeep, Bernhard, William A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882639/
https://ncbi.nlm.nih.gov/pubmed/20469885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp101717u
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