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Mechanisms of Strand Break Formation in DNA due to the Direct Effect of Ionizing Radiation: The Dependency of Free Base Release on the Length of Alternating CG Oligodeoxynucleotides

The question of how NA base sequence influences the yield of DNA strand breaks produced by the direct effect of ionizing radiation was investigated in a series of oligodeoxynucleotides of the form (d(CG)(n))(2) and (d(GC)(n))(2). The yields of free base release from X-irradiated DNA films containing...

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Main Authors: Sharma, Kiran K., Razskazovskiy, Yuriy, Purkayastha, Shubhadeep, Bernhard, William A.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791348/
https://ncbi.nlm.nih.gov/pubmed/19492855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp900803b
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