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Mechanisms of Direct Radiation Damage in DNA, Based on a Study of the Yields of Base Damage, Deoxyribose Damage, and Trapped Radicals in d(GCACGCGTGC)(2)

Dose–response curves were measured for the formation of direct-type DNA products in X-irradiated d(GCACGCGTGC)(2) prepared as dry films and as crystalline powders. Damage to deoxyribose (dRib) was assessed by HPLC measurements of strand break products containing 3′ or 5′ terminal phosphate and free...

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Detalhes bibliográficos
Main Authors: Swarts, Steven G., Gilbert, David C., Sharma, Kiran K., Razskazovskiy, Yuriy, Purkayastha, Shubhadeep, Naumenko, Katerina A., Bernhard, William A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791345/
https://ncbi.nlm.nih.gov/pubmed/17705640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR1058.1
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