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TGF-β-induced Myelin Peptide-Specific Regulatory T Cells Mediate Antigen-Specific Suppression of Induction of Experimental Autoimmune Encephalomyelitis

The low number of natural regulatory T cells (nTreg cells) in the circulation specific for a particular antigen and concerns about the bystander suppressive capacity of expanded nTregs presents a major clinical challenge for nTreg-based therapeutic treatment of autoimmune diseases. In the present st...

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Main Authors: Zhang, Hong, Podojil, Joseph R., Chang, Judy, Luo, Xunrong, Miller, Stephen D.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882517/
https://ncbi.nlm.nih.gov/pubmed/20483764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0904044
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