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Intrinsic and induced regulation of the age-associated onset of spontaneous experimental autoimmune encephalomyelitis

Multiple sclerosis (MS) is characterized by perivascular CNS infiltration of myelin-specific CD4(+) T cells and activated mononuclear cells. T cell receptor (TCR) transgenic mice on the SJL background specific for proteolipid protein (PLP)(139-151) (5B6 Tg mice) develop a high incidence of spontaneo...

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Bibliografiske detaljer
Main Authors: Zhang, Hong, Podojil, Joseph R., Luo, Xunrong, Miller, Stephen D.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853378/
https://ncbi.nlm.nih.gov/pubmed/18802066
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