Modulation of the Vitamin D3 response by cancer-associated mutant p53

The p53 gene is mutated in many human tumors. Cells of such tumors often contain abundant mutant p53 (mutp53) protein, which may contribute actively to tumor progression via a gain of function (GOF) mechanism. We applied ChIP-on-chip analysis and identified the VDR (vitamin D receptor) response elem...

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Autori principali: Stambolsky, Perry, Tabach, Yuval, Fontemaggi, Giulia, Weisz, Lilach, Maor-Aloni, Revital, Shiff, Idit, Kogan, Ira, Shay, Moshe, Kalo, Eyal, Blandino, Giovanni, Simon, Itamar, Oren, Moshe, Rotter, Varda
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882298/
https://ncbi.nlm.nih.gov/pubmed/20227041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2009.11.025
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