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Tau levels do not influence human ALS or motor neuron degeneration in the SOD1(G93A) mouse
BACKGROUND: The microtubule-associated protein tau is thought to play a pivotal role in neurodegeneration. Mutations in the tau coding gene MAPT are a cause of frontotemporal dementia, and the H1/H1 genotype of MAPT, giving rise to higher tau expression levels, is associated with progressive supranu...
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| Hlavní autoři: | , , , , , , , , , , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Academy of Neurology
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2882212/ https://ncbi.nlm.nih.gov/pubmed/20498436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e3181e042f7 |
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