Tau levels do not influence human ALS or motor neuron degeneration in the SOD1(G93A) mouse

BACKGROUND: The microtubule-associated protein tau is thought to play a pivotal role in neurodegeneration. Mutations in the tau coding gene MAPT are a cause of frontotemporal dementia, and the H1/H1 genotype of MAPT, giving rise to higher tau expression levels, is associated with progressive supranu...

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Autors principals: Taes, I., Goris, A., Lemmens, R., van Es, M.A., van den Berg, L.H., Chio, A., Traynor, B.J., Birve, A., Andersen, P., Slowik, A., Tomik, B., Brown, R.H., Shaw, C.E., Al-Chalabi, A., Boonen, S., Van Den Bosch, L., Dubois, B., Van Damme, P., Robberecht, W.
Format: Artigo
Idioma:Inglês
Publicat: American Academy of Neurology 2010
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882212/
https://ncbi.nlm.nih.gov/pubmed/20498436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e3181e042f7
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