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Posttranslational Modification of p53: Cooperative Integrators of Function
The p53 protein is modified by as many as 50 individual posttranslational modifications. Many of these occur in response to genotoxic or nongenotoxic stresses and show interdependence, such that one or more modifications can nucleate subsequent events. This interdependent nature suggests a pathway t...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Cold Spring Harbor Laboratory Press
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2882125/ https://ncbi.nlm.nih.gov/pubmed/20457558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a000950 |
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