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Posttranslational Modification of p53: Cooperative Integrators of Function

The p53 protein is modified by as many as 50 individual posttranslational modifications. Many of these occur in response to genotoxic or nongenotoxic stresses and show interdependence, such that one or more modifications can nucleate subsequent events. This interdependent nature suggests a pathway t...

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Bibliografiska uppgifter
Huvudupphovsmän: Meek, David W., Anderson, Carl W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cold Spring Harbor Laboratory Press 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882125/
https://ncbi.nlm.nih.gov/pubmed/20457558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a000950
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