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Posttranslational Modification of p53: Cooperative Integrators of Function

The p53 protein is modified by as many as 50 individual posttranslational modifications. Many of these occur in response to genotoxic or nongenotoxic stresses and show interdependence, such that one or more modifications can nucleate subsequent events. This interdependent nature suggests a pathway t...

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Detalhes bibliográficos
Main Authors: Meek, David W., Anderson, Carl W.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882125/
https://ncbi.nlm.nih.gov/pubmed/20457558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a000950
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