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Plk1-dependent phosphorylation of FoxM1 regulates a transcriptional programme required for mitotic progression

Proper control of entry into and progression through mitosis is essential for normal cell proliferation and the maintenance of genome stability1–4. The mammalian mitotic kinase Pololike kinase 1 (Plk1) is involved in multiple stages of mitosis5. Here we report that Forkhead Box M1 (FoxM1), a substra...

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Autors principals: Fu, Zheng, Malureanu, Liviu, Huang, Jun, Wang, Wei, Li, Hao, van Deursen, Jan M., Tindall, Donald J., Chen, Junjie
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882053/
https://ncbi.nlm.nih.gov/pubmed/19160488
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