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Mitotic entry: Non-genetic heterogeneity exposes the requirement for Plk1

The quest to develop novel antimitotic chemotherapy agents has led to the generation of several small molecule inhibitors targeting Plk1, a protein kinase required for multiple aspects of cell division. Previous studies have shown that upon exposure to Plk1 inhibitors, cells enter mitosis, delay bri...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Aspinall, Claire F., Zheleva, Daniella, Tighe, Anthony, Taylor, Stephen S.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742190/
https://ncbi.nlm.nih.gov/pubmed/26472023
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