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A mutation in H5 haemagglutinin that conferred human receptor recognition is not maintained stably during duck passage
A/Hong Kong/213/97 (HK213; H5N1), isolated from a human, binds to both avian- and human-type receptors, due to a haemagglutinin (HA) mutation probably acquired during adaptation to humans. Duck passage of this virus conferred lethality in ducks. Sequence analyses of the duck-passaged virus revealed...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for General Microbiology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2881941/ https://ncbi.nlm.nih.gov/pubmed/20130132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.018572-0 |
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