Replication-incompetent influenza A viruses that stably express a foreign gene

A biologically contained influenza A virus that stably expresses a foreign gene can be effectively traced, used to generate a novel multivalent vaccine and have its replication easily assessed, all while satisfying safety concerns regarding pathogenicity or reversion. This study generated a PB2-knoc...

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Bibliografiske detaljer
Main Authors: Ozawa, Makoto, Victor, Sylvia T., Taft, Andrew S., Yamada, Shinya, Li, Chengjun, Hatta, Masato, Das, Subash C., Takashita, Emi, Kakugawa, Satoshi, Maher, Eileen A., Neumann, Gabriele, Kawaoka, Yoshihiro
Format: Artigo
Sprog:Inglês
Udgivet: Society for General Microbiology 2011
Fag:
Animal
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3352570/
https://ncbi.nlm.nih.gov/pubmed/21880840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.037648-0
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