The Zn3 Domain of Human Poly(ADP-ribose) Polymerase-1 (PARP-1) Functions in Both DNA-dependent Poly(ADP-ribose) Synthesis Activity and Chromatin Compaction

PARP-1 is involved in multiple cellular processes, including transcription, DNA repair, and apoptosis. PARP-1 attaches ADP-ribose units to target proteins, including itself as a post-translational modification that can change the biochemical properties of target proteins and mediate recruitment of p...

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Detaylı Bibliyografya
Asıl Yazarlar: Langelier, Marie-France, Ruhl, Donald D., Planck, Jamie L., Kraus, W. Lee, Pascal, John M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2010
Konular:
Gene Regulation
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881810/
https://ncbi.nlm.nih.gov/pubmed/20388712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.105668
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