Nuclear Export and Centrosome Targeting of the Protein Phosphatase 2A Subunit B56α: ROLE OF B56α IN NUCLEAR EXPORT OF THE CATALYTIC SUBUNIT

Protein phosphatase (PP) 2A is a heterotrimeric enzyme regulated by specific subunits. The B56 (or B′/PR61/PPP2R5) class of B-subunits direct PP2A or its substrates to different cellular locations, and the B56α, -β, and -ϵ isoforms are known to localize primarily in the cytoplasm. Here we studied th...

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Detalhes bibliográficos
Main Authors: Flegg, Cameron P., Sharma, Manisha, Medina-Palazon, Cahora, Jamieson, Cara, Galea, Melanie, Brocardo, Mariana G., Mills, Kate, Henderson, Beric R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881738/
https://ncbi.nlm.nih.gov/pubmed/20378546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.093294
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