Loading...
Rac1 augments Wnt signaling by stimulating β-catenin–lymphoid enhancer factor-1 complex assembly independent of β-catenin nuclear import
β-Catenin transduces the Wnt signaling pathway and its nuclear accumulation leads to gene transactivation and cancer. Rac1 GTPase is known to stimulate β-catenin-dependent transcription of Wnt target genes and we confirmed this activity. Here we tested the recent hypothesis that Rac1 augments Wnt si...
Na minha lista:
| Udgivet i: | J Cell Sci |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Company of Biologists
2015
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4657330/ https://ncbi.nlm.nih.gov/pubmed/26403202 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.167742 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|