Structures of PHR domains from Mus musculus Phr1 (Mycbp2) explain the loss of function mutation (Gly1092→Glu) of the C. elegans ortholog RPM-1

PHR (Pam-Highwire-RPM-1) proteins are conserved, large multi-domain E3 ubiquitin ligases with modular architecture. PHR proteins presynaptically control synaptic growth and axon guidance and postsynaptically regulate endocytosis of glutamate receptors. Dysfunction of neuronal ubiquitin-mediated prot...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Sampathkumar, Parthasarathy, Ozyurt, Sinem A., Miller, Stacy, Bain, Kevin T., Rutter, Marc E., Gheyi, Tarun, Abrams, Benjamin, Wang, Yingchun, Atwell, Shane, Luz, John G., Thompson, Devon A., Wasserman, Stephen R., Spencer Emtage, J., Park, Eunchan C., Rongo, Christopher, Jin, Yishi, Klemke, Richard L., Michael Sauder, J., Burley, Stephen K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881670/
https://ncbi.nlm.nih.gov/pubmed/20156452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.02.017
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi