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Allenamide Hydro-Hydroxyalkylation: 1,2-Aminoalcohols via Ruthenium Catalyzed Carbonyl anti-Aminoallylation

[Image: see text] Exposure of alcohols to allenamides in the presence of RuHCl(CO)(PPh(3))(3) and dippf [dippf = bis(diisopropylphosphino)ferrocene] results in hydrogen transfer to generate aldehyde-allylruthenium pairs, which engage in C-C coupling to form products of carbonyl aminoallylation as si...

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Autors principals: Zbieg, Jason R., McInturff, Emma L., Krische, Michael J.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881554/
https://ncbi.nlm.nih.gov/pubmed/20459077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol1007235
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