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MOTIF-EM: an automated computational tool for identifying conserved regions in CryoEM structures

We present a new, first-of-its-kind, fully automated computational tool MOTIF-EM for identifying regions or domains or motifs in cryoEM maps of large macromolecular assemblies (such as chaperonins, viruses, etc.) that remain conformationally conserved. As a by-product, regions in structures that are...

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Détails bibliographiques
Auteurs principaux: Saha, Mitul, Levitt, Michael, Chiu, Wah
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881380/
https://ncbi.nlm.nih.gov/pubmed/20529921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq195
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