Chargement en cours...
Improved docking, screening and selectivity prediction for small molecule nuclear receptor modulators using conformational ensembles
Nuclear receptors (NRs) are ligand dependent transcriptional factors and play a key role in reproduction, development, and homeostasis of organism. NRs are potential targets for treatment of cancer and other diseases such as inflammatory diseases, and diabetes. In this study, we present a comprehens...
Enregistré dans:
| Auteurs principaux: | , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Springer Netherlands
2010
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2881208/ https://ncbi.nlm.nih.gov/pubmed/20455005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10822-010-9362-4 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|