Φορτώνει......
Improved docking, screening and selectivity prediction for small molecule nuclear receptor modulators using conformational ensembles
Nuclear receptors (NRs) are ligand dependent transcriptional factors and play a key role in reproduction, development, and homeostasis of organism. NRs are potential targets for treatment of cancer and other diseases such as inflammatory diseases, and diabetes. In this study, we present a comprehens...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Springer Netherlands
2010
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2881208/ https://ncbi.nlm.nih.gov/pubmed/20455005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10822-010-9362-4 |
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