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Hydroxycarbamide-Induced Changes in E/beta Thalassemia Red Blood Cells

In thalassemia, fetal hemoglobin (HbF) augmentation with hydroxycarbamide (also known as hydroxyurea) is not always successful. The expected parallel effects on RBC membrane deformability, cell hydration and membrane phospholipid organization, all important for extending RBC life span and increasing...

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Detalhes bibliográficos
Main Authors: Sylvia, Singer T., Elliott, Vichinsky, Sandra, Larkin, Nancy, Olivieri, Nancy, Sweeters, Frans, Kuypers A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881160/
https://ncbi.nlm.nih.gov/pubmed/18821710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.21266
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