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Hydroxycarbamide-Induced Changes in E/beta Thalassemia Red Blood Cells

In thalassemia, fetal hemoglobin (HbF) augmentation with hydroxycarbamide (also known as hydroxyurea) is not always successful. The expected parallel effects on RBC membrane deformability, cell hydration and membrane phospholipid organization, all important for extending RBC life span and increasing...

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Main Authors: Sylvia, Singer T., Elliott, Vichinsky, Sandra, Larkin, Nancy, Olivieri, Nancy, Sweeters, Frans, Kuypers A.
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881160/
https://ncbi.nlm.nih.gov/pubmed/18821710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.21266
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