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The thrombin receptor extracellular domain contains sites crucial for peptide ligand-induced activation.

A thrombin receptor (TR) demonstrating a unique activation mechanism has recently been isolated from a megakaryocytic (Dami) cell line. To further study determinants of peptide ligand-mediated activation phenomenon, we have isolated, cloned, and stably expressed the identical receptor from a human u...

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Dettagli Bibliografici
Pubblicato in:J Clin Invest
Autori principali: Bahou, W F, Coller, B S, Potter, C L, Norton, K J, Kutok, J L, Goligorsky, M S
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1993
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288114/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8386186/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116344
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