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Feed-Forward Regulation of a Cell Fate Determinant by an RNA-Binding Protein Generates Asymmetry in Yeast

Saccharomyces cerevisiae can divide asymmetrically so that the mother and daughter cells have different fates. We show that the RNA-binding protein Khd1 regulates asymmetric expression of FLO11 to determine daughter cell fate during filamentous growth. Khd1 represses transcription of FLO11 indirectl...

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Autores principales: Wolf, Joshua J., Dowell, Robin D., Mahony, Shaun, Rabani, Michal, Gifford, David K., Fink, Gerald R.
Formato: Artigo
Lenguaje:Inglês
Publicado: Genetics Society of America 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881133/
https://ncbi.nlm.nih.gov/pubmed/20382833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.110.113944
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