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Brachyury controls Ciona notochord fate as part of a feed-forward network

The notochord is a defining feature of the chordates. The transcription factor Brachyury (Bra) is a key regulator of notochord fate but here we show that it is not a unitary master regulator in the model chordate Ciona. Ectopic Bra expression only partially reprograms other cell types to a notochord...

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Détails bibliographiques
Publié dans:Development
Auteurs principaux: Reeves, Wendy M., Shimai, Kotaro, Winkley, Konner M., Veeman, Michael T.
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists Ltd 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7875503/
https://ncbi.nlm.nih.gov/pubmed/33419874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.195230
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