Comprehensive profiling of DNA methylation in colorectal cancer reveals subgroups with distinct clinicopathological and molecular features

BACKGROUND: Most previous studies of the CpG island methylator phenotype (CIMP) in colorectal cancer (CRC) have been conducted on a relatively small numbers of CpG sites. In the present study we performed comprehensive DNA methylation profiling of CRC with the aim of characterizing CIMP subgroups. M...

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Detalhes bibliográficos
Main Authors: Ang, Pei Woon, Loh, Marie, Liem, Natalia, Lim, Pei Li, Grieu, Fabienne, Vaithilingam, Aparna, Platell, Cameron, Yong, Wei Peng, Iacopetta, Barry, Soong, Richie
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880997/
https://ncbi.nlm.nih.gov/pubmed/20492682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-227
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