DNA methylation subgroups and the CpG island methylator phenotype in gastric cancer: a comprehensive profiling approach

BACKGROUND: Methylation-induced silencing of promoter CpG islands in tumor suppressor genes plays an important role in human carcinogenesis. In colorectal cancer, the CpG island methylator phenotype (CIMP) is defined as widespread and elevated levels of DNA methylation and CIMP+ tumors have distinct...

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Detalhes bibliográficos
Main Authors: Loh, Marie, Liem, Natalia, Vaithilingam, Aparna, Lim, Pei Li, Sapari, Nur Sabrina, Elahi, Eiram, Mok, Zuan Yu, Cheng, Chee Leong, Yan, Benedict, Pang, Brendan, Salto-Tellez, Manuel, Yong, Wei Peng, Iacopetta, Barry, Soong, Richie
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986689/
https://ncbi.nlm.nih.gov/pubmed/24674026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-14-55
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