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Structure of the Minimal Interface Between ApoE and LRP

Clusters of complement-type ligand binding repeats in the LDL receptor family are thought to mediate the interactions with their various ligands. Apolipoprotein E, a key ligand for cholesterol homeostasis, has been shown to interact with LRP through these clusters. The segment comprising the recepto...

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Библиографические подробности
Главные авторы: Guttman, Miklos, Prieto, J. Helena, Handel, Tracy M., Domaille, Peter J., Komives, Elizabeth A.
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880916/
https://ncbi.nlm.nih.gov/pubmed/20303980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.03.022
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