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Enantioselective synthesis of bicylco[3.2.1]octan-8-ones using a tandem Michael-Henry reaction

Bicyclo[3.2.1]octan-8-ones have been prepared from a tandem Michael-Henry reaction between cyclohexane-1,2-diones and nitroalkenes using a quinine-derived thiourea as the catalyst. Although four stereogenic centers were created during the reaction, only two diastereomers were obtained in good diaste...

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Autori principali: Ding, Derong, Zhao, Cong-Gui, Guo, Qunsheng, Arman, Hadi
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880813/
https://ncbi.nlm.nih.gov/pubmed/20532185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2010.04.044
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