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Enantioselective Synthesis of β-(3-Hydroxypyrazol-1-yl)ketones Using An Organocatalyzed Michael Addition Reaction

[Image: see text] β-(3-Hydroxypyrazol-1-yl)ketones have been prepared in high yields and excellent enantioselectivities (94–98% ee) via a Michael addition reaction between 2-pyrazolin-5-ones and aliphatic acyclic α,β-unsaturated ketones using 9-epi-9-amino-9-deoxyquinine as the catalyst. These resul...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gogoi, Sanjib, Zhao, Cong-Gui, Ding, Derong
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752151/
https://ncbi.nlm.nih.gov/pubmed/19415906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol900538q
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