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Organocatalyzed asymmetric Michael reaction of β-aryl-α-ketophosphonates and nitroalkenes

The first enantioselective Michael reaction of β-aryl-α-ketophosphonates and nitroalkenes has been brealized by using a new bifunctional Takemoto-type thiourea catalyst. The primary Michael adducts obtained were converted in situ to the corresponding amides through the aminolysis. High yields, excel...

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Detalhes bibliográficos
Main Authors: Guang, Jie, Zhao, John Cong-Gui
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3810965/
https://ncbi.nlm.nih.gov/pubmed/24187390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2013.08.015
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