Effectiveness of Novel Borane−Phosphine Complexes in Inhibiting Cell Death Depends on the Source of Superoxide Production Induced by Blockade of Mitochondrial Electron Transport

[Image: see text] Central neurons undergo cell death after axotomy. One of the signaling pathways for this process is oxidative modification of one or more critical sulfhydryls in association with superoxide generation within mitochondria. Agents that reduce oxidized sulfhydryls are neuroprotective...

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Autors principals: Seidler, Emily A., Lieven, Christopher J., Thompson, Alex F., Levin, Leonard A.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2009
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880810/
https://ncbi.nlm.nih.gov/pubmed/20532184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn900024r
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