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Bfl-1/A1 functions, similar to Mcl-1, as a selective tBid and Bak antagonist
The prosurvival Bcl-2-family member Bfl-1/A1 is a transcriptional target of nuclear factor-κB (NF-κB) that is overexpressed in many human tumors and is a means by which NF-κB inhibits apoptosis, but its mode of action is controversial. To better understand how Bfl-1 functions, we investigated its in...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2880719/ https://ncbi.nlm.nih.gov/pubmed/17724464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1210771 |
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