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Motifs of VDAC2 required for mitochondrial Bak import and tBid-induced apoptosis
Voltage-dependent anion channel (VDAC) proteins are major components of the outer mitochondrial membrane. VDAC has three isoforms with >70% sequence similarity and redundant roles in metabolite and ion transport. However, only Vdac2(−/−) (V2(−/−)) mice are embryonic lethal, indicating a unique an...
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| Yayımlandı: | Proc Natl Acad Sci U S A |
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| Asıl Yazarlar: | , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
National Academy of Sciences
2015
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4611654/ https://ncbi.nlm.nih.gov/pubmed/26417093 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1510574112 |
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