A deficiency in Mdm2 binding protein (MTBP) inhibits Myc-induced B cell proliferation and lymphomagenesis

Mdm2 binding protein (MTBP) has been implicated in cell cycle arrest and the Mdm2-p53 tumor suppressor pathway through its interaction with Mdm2. To determine the function of MTBP in tumorigenesis and its potential role in the Mdm2-p53 pathway, we crossed Mtbp deficient mice to Eµ-myc transgenic mic...

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Detalhes bibliográficos
Main Authors: Odvody, Jessica, Vincent, Tiffaney, Arrate, Maria Pia, Grieb, Brian, Wang, Shuo, Garriga, Judit, Lozano, Guillermina, Iwakuma, Tomoo, Haines, Dale S., Eischen, Christine M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880662/
https://ncbi.nlm.nih.gov/pubmed/20305689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.82
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