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MicroRNA Biogenesis is Required for Myc-Induced B cell Lymphoma Development and Survival

Many tumor cells express globally reduced levels of microRNAs (miRNAs), suggesting that decreased miRNA expression in pre-malignant cells contributes to their tumorigenic phenotype. In support of this, Dicer, an RNAse III-like enzyme that controls maturation of miRNA, was recently shown to function...

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Detalhes bibliográficos
Main Authors: Arrate, Maria Pia, Vincent, Tiffaney, Odvody, Jessica, Kar, Rekha, Jones, Stephen N., Eischen, Christine M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906119/
https://ncbi.nlm.nih.gov/pubmed/20587524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-4736
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