Inhibition of a Plasmodium vinckei cysteine proteinase cures murine malaria.
Intraerythrocytic malaria parasites degrade hemoglobin as a principal source of amino acids for parasite protein synthesis. We have previously identified a Plasmodium falciparum trophozoite cysteine proteinase as a putative hemoglobinase and shown that specific inhibitors of this proteinase block th...
שמור ב:
| הוצא לאור ב: | J Clin Invest |
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| Principais autores: | , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Clinical Investigation
1993
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288059/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8450035/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116262 |
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