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Inhibition of a Plasmodium vinckei cysteine proteinase cures murine malaria.

Intraerythrocytic malaria parasites degrade hemoglobin as a principal source of amino acids for parasite protein synthesis. We have previously identified a Plasmodium falciparum trophozoite cysteine proteinase as a putative hemoglobinase and shown that specific inhibitors of this proteinase block th...

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Bibliografiske detaljer
Main Authors: Rosenthal, P J, Lee, G K, Smith, R E
Format: Artigo
Sprog:Inglês
Udgivet: 1993
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC288059/
https://ncbi.nlm.nih.gov/pubmed/8450035
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