Inhibition of a Plasmodium vinckei cysteine proteinase cures murine malaria.

Intraerythrocytic malaria parasites degrade hemoglobin as a principal source of amino acids for parasite protein synthesis. We have previously identified a Plasmodium falciparum trophozoite cysteine proteinase as a putative hemoglobinase and shown that specific inhibitors of this proteinase block th...

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Bibliografiske detaljer

Udgivet i:	J Clin Invest
Principais autores:	Rosenthal, P J, Lee, G K, Smith, R E
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Clinical Investigation 1993
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288059/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8450035/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116262
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